1 paper1 finding
Heterochronic parabiosis
mixedin mice1
Heterochronic parabiosis is associated with aging signatures in mice.
“heterochronic parabiosis reprograms the mouse brain transcriptome by shifting aging signatures in multiple cell types”
Animalsbrain
Nature aging9 Mar 2023
A three-region model scored 0.81 versus 0.79 for a whole-brain model on a measure of how well it ranked death risk.A three-region model scored 0.81 versus 0.79 for a whole-brain model on a measure of how well it ranked death risk.
Researchers used transcriptomic models, DNA methylation, and images across multiple human cohorts to infer tissue-specific biological age and hallmark burdens.Researchers used transcriptomic models, DNA methylation, and images across multiple human cohorts to infer tissue-specific biological age and hallmark burdens.