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Dysregulated NF-κB dynamics impair proteostasis and drive premature differentiation in aging B cell development
Experiments in miceProteostasis
Papers on aged B cells
17 papers
Tuesday, August 11
Friday, May 1
bioRxiv
Repetitive DNA-resolved epigenomics maps chromatin rewiring during aging and malignant transformation
Preprint: computational studyEpigenomics
Monday, October 20
Saturday, October 11
Aging Cell
Bone Loss and TLR4 Signals Contribute Independently to B Lineage Aging
Experiments in miceTLR4
Saturday, August 23
Wednesday, July 2
Frontiers in Immunology
Differential metabolic pathways underlie THC- and CBD-mediated inhibition of B-cell activation in both young and aged mice
Experiments in mouse cellsBlood and immune system
Sunday, August 6
Thursday, June 8
Saturday, October 23
Frontiers in Immunology
The Dynamics of B Cell Aging in Health and Disease
ReviewBlood and immune system
Thursday, July 2
The Journals of Gerontology, Series A
Unique Transcriptome Changes in Peripheral B Cells Revealed by Comparing Age Groups From Naive or Vaccinated Mice, Including snoRNA and Cdkn2a
Experiments in animalsMechanisms
Wednesday, July 10
Saturday, April 13
bioRxiv
Aging induces Nlrp3 inflammasome dependent adipose B cell expansion to impair metabolic homeostasis
Preprint: experiments in miceNLRP3 inflammasome
Friday, August 18
Cell Death & Disease
Altered marginal zone and innate-like B cells in aged senescence-accelerated SAMP8 mice with defective IgG1 responses
Experiments in miceImmune response
Tuesday, January 24
Mechanisms of Ageing and Development
Obesity induces pro-inflammatory B cells and impairs B cell function in old mice
Experiments in miceInflammation
Saturday, December 10
Experimental Gerontology
Human peripheral late/exhausted memory B cells express a senescent-associated secretory phenotype and preferentially utilize metabolic signaling pathways
Cohort study in peoplep38 MAPK signaling
Saturday, November 5
European Journal of Immunology
Aged B cells alter immune regulation of allografts in mice
Experiments in miceImmune response
Saturday, March 12
Oncotarget
Age-related changes in the transcriptome of antibody-secreting cells
Experiments in miceMechanisms