Age-related gene expression

1. Caloric restriction decreases age-related gene expression in mice.

   “Caloric restriction (CR) inhibited age-related expression of these genes in both tissues.”

   Animalsheart

   Gene expression profiling of aging in multiple mouse strains: identification of aging biomarkers and impact of dietary antioxidants

   Aging cell·Jun 25, 2009

More on Caloric restriction

1. Sex dimorphism is associated with age-related gene expression in mice.

   “the vast majority of age-related genes were sex and tissue specific”

   Animalsacross liver, gastrocnemius muscle, and white adipose tissue

   Sex dimorphism and tissue specificity of gene expression changes in aging mice

   Biology of sex differences·Oct 31, 2024

1. Egg removal is associated with age-related gene expression in B. terrestris.

   “treatment and control queens differed in age-related gene expression based on mRNA-seq in both their overall expression profiles and the expression of ageing-related genes.”

   Model organismsqueens; differences principally related to relative rather than chronological agefemales

   Eusocial insect queens show costs of reproduction and transcriptomic signatures of reduced longevity

   bioRxiv (Cold Spring Harbor Laboratory)·Mar 20, 2022Preprint

More on Egg removal