Age-corrected brain age gap

1 paper1 finding

Humans1

Associations

1

Major depressive disorder

upin humans1

1 study

Major depressive disorder is associated with age-corrected brain age gap in humans (+2.01 years versus healthy controls).
“MDD was associated with significantly elevated cBAG compared with healthy controls (mean difference + 2.01 years).”
HumansMedication-free, current depressive episode; compared with matched healthy controlsbrain
Age-dependent acceleration of structural brain aging in medication-free major depressive disorder linked to neuroanatomical phenotype findings from COORDINATE-MDD consortium
medRxiv : the preprint server for health sciences8 Apr 2026Preprint

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