Adipose stem and progenitor cell abundance

Vascular niche deterioration decreases adipose stem and progenitor cell abundance in silico.

“a middle-aged, male-specific decline in adipose stem and progenitor cells, driven by vascular niche deterioration and disrupted VEGF–VEGFR signaling”

In silicoDisrupted VEGF–VEGFR signalingadipose tissuemales

PersonaAI: An Interactive Agentic-AI Framework for Autonomous Hypothesis Generation and Validation in Aging

bioRxiv (Cold Spring Harbor Laboratory)·20 Jan 2026Preprint