AD composite brain volume

Mild behavioral impairment-apathy is associated with AD composite brain volume in humans (β = -3.33, 95% CI -4.66-(-2.00), p < 0.001).

“MBI‐apathy status was significantly associated with lower average AD composite thickness score (β = ‐0.40; 95% CI = ‐0.74‐(‐0.05); p = 0.024), total AD composite volume (β = ‐3.33; 95% CI = ‐4.66‐(‐2.00); p < 0.001)”

Humansdementia-free individualsbrainn = 446

Regional Brain Volume and Thickness in Mild Behavioral Impairment‐Apathy

AAIC 2025 abstract·24 Dec 2025