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Acetylated SMC3-marked cohesive cohesin

Biomarker

1 paper2 findings

  • Humans1

Associations

1

Maternal age

downin humans1downin mice1

1 study

  1. Maternal age is associated with acetylated SMC3-marked cohesive cohesin in humans.

    “age-dependent depletion of the acetylated SMC3-marked cohesive subpopulation of cohesin from oocytes at the dormant primordial follicle stage in both mice and humans.”

    Humansdormant primordial follicle stageoocytefemales

    Chromosome Ageing Occurs at the Primordial Follicle Stage in both Mouse and Human Oocytes

    bioRxiv (Cold Spring Harbor Laboratory)18 Jul 2025Preprint

  2. Maternal age is associated with acetylated SMC3-marked cohesive cohesin in mice.

    “age-dependent depletion of the acetylated SMC3-marked cohesive subpopulation of cohesin from oocytes at the dormant primordial follicle stage in both mice and humans.”

    Animalsdormant primordial follicle stageoocytefemales

    Chromosome Ageing Occurs at the Primordial Follicle Stage in both Mouse and Human Oocytes

    bioRxiv (Cold Spring Harbor Laboratory)18 Jul 2025Preprint

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