9-HOTrE/alpha-linolenic acid ratio

1. Longevity Relatives Count score is associated with 9-HOTrE/alpha-linolenic acid ratio in humans.

   “Lipid mediators, including elevated 6-keto-PGF1a and reduced 9-HOTrE/alpha-linolenic acid ratio, reflected preserved endothelial homeostasis and attenuated inflammatory signaling.”

   Humansfamilial longevityplasman = 495

   Multi-omics integration identifies metabolic and inflammatory pathways underlying familial longevity

   medRxiv·15 May 2026Preprint

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