5hmCG

5hmCG is associated with cell-type-specific gene expression in mice.

“5hmCG accumulates globally but is selectively enriched at open chromatin loci, aligning with the upregulation of cell-type-specific genes in distinct brain cell types.”

Animalsduring aging; at open chromatin locibrain

Single-cell Characterization of DNA Hydroxymethylation of the Mouse Brain During Aging

bioRxiv (Cold Spring Harbor Laboratory)·1 Jun 2025Preprint