Nature Communications·8 OctCBX4 stabilizes NEUROD1 through SUMO-ubiquitin crosstalk to delay β-cell senescenceExperiments in miceCellular senescencePaper
FASEB Journal·26 SepNR4A1-Driven Granulosa Cell Ferroptosis Contributes to Obesity-Related Ovarian Dysfunction and Metformin-Mediated Ovarian ProtectionExperiments in miceMetforminPaper
Journal of Renal Nutrition·21 SepLong-Term AST and AST/ALT Ratio Exposure Reflects Risk of Low Skeletal Muscle Mass in Maintenance Hemodialysis: A Real-World Cohort StudyStudy in peopleBiomarkersPaper
Research Square·11 SepExploring Determinants of Functional Independence in Ischemic Stroke: A Hierarchical and Interaction Effects Modeling ApproachPreprint: study in peoplePopulationsPaper
Journal of Endocrinological Investigation·10 SepCumulative metabolic burden and urinary albumin-to-creatinine ratio in non-diabetic adults: a nationwide population-based studyCross-sectional study of 3,335 peoplePopulationsPaper
American Journal of Transplantation·8 SepNLR family pyrin domain containing 3-mediated Kupffer cell pyroptosis aggravates ischemia-reperfusion injury after aging donor liver transplantation through CD38-nicotinamide adenine dinucleotide⁺-sirtuin 1-dependent acetylation of estrogen-related receptor αExperiments in micePyroptosisPaper
Frontiers in Public Health·8 SepSocial cognition assessment in Chinese adults with mild cognitive impairment: a scoping reviewSystematic review of observational studiesMild cognitive impairmentPaper
Clinical & Translational Oncology·6 SepCancer risk and mortality assessment in the overweight population: evaluation of single and integrated models based on inflammatory markersCohort study of 11,348 peopleCancerPaper
Investigative Ophthalmology & Visual Science·4 SepCumulative Loss of Inner Retinal Neurons in Healthy and Glaucoma SubjectsCohort study in peopleEyePaper
Military Medical Research·1 SepGastroAlert: a multimodal epigenetic blood test for early detection of gastric cancer using cell-free DNACase-control study of 149 peopleGastric cancerPaper
Pharmacoepidemiology and Drug Safety·29 AugDementias in Older Women With Early-Stage HER2-Negative Breast Cancer Treated With Anthracycline Plus Taxane Versus Taxane-Based Chemotherapy RegimensCohort study of 14,079 peopleAlzheimer's disease and related dementiasPaper
Diabetes Care·24 AugA Randomized Placebo-Controlled Trial of HTD1801 Monotherapy in Participants With Type 2 DiabetesTrial in peopleInterventionsPaper
Public Health Reports·24 AugCardiovascular-Related Death Among Women With Breast Cancer in the United States: Do We Need a Better Approach for Estimating Rates?Computational studyPopulationsPaper
American Heart Journal Plus·23 AugThe prognostic value of combined TyG and SIRI categories for cardiovascular disease and all-cause mortality among adults: Evidence from the NHANES 1999-2010Cohort study of 11,010 peopleCardiovascular diseasePaper
Journal of Renal Nutrition·21 AugIndoxyl Sulfate and Soluble Prorenin Receptor Axis Contributes to Sarcopenia in Maintenance Hemodialysis Patients by Inducing Mitochondrial Damage: An Integrated Clinical and Experimental StudyCross-sectional study of 141 peopleMitochondrionPaper
The American Journal of Geriatric Psychiatry·20 AugThe Longitudinal Relationships Between Cognitive Impairment and Depression in Older Adults: A Cross-Lagged Panel Network AnalysisCohort study of 6,297 peopleCognitive impairmentPaper
Frontiers in Endocrinology·20 AugSGLT2 inhibition, uric acid and inflammation in glycemic burden-related progression of cardiac autonomic neuropathy in type 2 diabetes mellitus: insights from machine learning and mediation analysisCohort study of 293 peopleUric acidPaper
Neurochemistry International·13 AugOsthol ameliorates Alzheimer's disease-associated cognitive impairment by targeting the estrogen-cholinergic axis in age-stratified female 3×Tg-AD miceExperiments in miceCognitive impairmentPaper
Frontiers in Immunology·13 AugBeyond hormone deficiency: a framework for endocrine-immune-niche integration in aging skeletal muscle regenerationComputational studyMusclePaper
Molecules·13 AugPharmacological Effects and Molecular Mechanisms of Lignans in the Treatment of Alzheimer's DiseaseReviewInterventionsPaper