Papers by S Yan

111 results

  1. bioRxiv

    Aging muscle and Alzheimer's brain share inflammatory signals

    Analysing datasets from 23 muscle donors and 30 early-progression brain donors, researchers identified matching inflammatory gene pathways across tissues.Analysing datasets from 23 muscle donors and 30 early-progression brain donors, researchers identified matching inflammatory gene pathways across tissues.

    Preprint: computational studyInflammation
  1. medRxiv

    Replacing sitting with brisk activity linked to lower AF odds in US

    In the REGARDS cohort, substituting 30 sedentary minutes with moderate-to-vigorous activity yielded an odds ratio of 0.80 for atrial fibrillation, while light activity…In the REGARDS cohort, substituting 30 sedentary minutes with moderate-to-vigorous activity yielded an odds ratio of 0.80 for atrial fibrillation, while light activity showed no association.

    Preprint: cohort study of 86,096 peoplePopulations
  2. BMC Public Health

    Higher neuroticism links to broad disease risks in Chinese adults

    In 25,041 Chinese adults, high neuroticism scores were linked to 1.17- to 1.81-fold higher risks of major physical and mental conditions compared to low scores.In 25,041 Chinese adults, high neuroticism scores were linked to 1.17- to 1.81-fold higher risks of major physical and mental conditions compared to low scores.

    Cohort study of 25,041 peoplePopulations
  3. Heart, Lung & Circulation

    Cardiometabolic index is linked to higher mortality risk

    In 17,922 US adults, elevated cardiometabolic index was linked to higher all-cause mortality with a hazard ratio of 1.35, showing stronger associations below age 60.In 17,922 US adults, elevated cardiometabolic index was linked to higher all-cause mortality with a hazard ratio of 1.35, showing stronger associations below age 60.

    Cohort study of 17,922 peopleCardiometabolic index
  4. Preventive Medicine

    Poor sleep patterns are linked to higher osteoporosis risk

    In 63,083 UK adults, short sleep had a hazard ratio of 1.16, irregular sleep 1.21, and low sleep efficiency 1.23 for incident osteoporosis.In 63,083 UK adults, short sleep had a hazard ratio of 1.16, irregular sleep 1.21, and low sleep efficiency 1.23 for incident osteoporosis.

    Cohort study of 63,083 peopleOsteoporosis
  5. medRxiv

    Biological age uncertainty independently predicts mortality and health decline in humans

    Researchers derived biological age uncertainty across UK Biobank participants, finding that higher uncertainty reflects reduced physiological coherence and predicts worse…Researchers derived biological age uncertainty across UK Biobank participants, finding that higher uncertainty reflects reduced physiological coherence and predicts worse health outcomes.

    Preprint: cohort study of 450,000 peopleBiomarkers