173 results
In mice, genetically removing the protein reduced signs of cellular aging across multiple tissues and limited hallmarks of blood stem cell aging.In mice, genetically removing the protein reduced signs of cellular aging across multiple tissues and limited hallmarks of blood stem cell aging.
In laboratory experiments, roflumilast and rolipram lengthened roundworm lifespan by activating a signalling pathway that improved mitochondrial function and alleviated…In laboratory experiments, roflumilast and rolipram lengthened roundworm lifespan by activating a signalling pathway that improved mitochondrial function and alleviated oxidative stress.
In 1,688 older adults in China, an index tracking uneven aging across five routine blood markers was associated with steeper cognitive decline over three years.In 1,688 older adults in China, an index tracking uneven aging across five routine blood markers was associated with steeper cognitive decline over three years.
In two prospective cohorts, each standard deviation increase in estimated glucose disposal rate was associated with a 40% lower risk of multiple cardiometabolic diseases.In two prospective cohorts, each standard deviation increase in estimated glucose disposal rate was associated with a 40% lower risk of multiple cardiometabolic diseases.
A randomised, double-blind trial also found changes in gut bacteria, including suppression of bacteria that produce an enzyme involved in processing bile acids.A randomised, double-blind trial also found changes in gut bacteria, including suppression of bacteria that produce an enzyme involved in processing bile acids.
An observational analysis of 18,553 people aged 11 and older across three US cohorts linked persistent isolation and loneliness to poorer memory scores.An observational analysis of 18,553 people aged 11 and older across three US cohorts linked persistent isolation and loneliness to poorer memory scores.
In a randomized trial, 12 weeks of the mind-body exercise lowered systolic blood pressure by 7.2 mmHg compared with habitual lifestyle.In a randomized trial, 12 weeks of the mind-body exercise lowered systolic blood pressure by 7.2 mmHg compared with habitual lifestyle.
Hobby engagement was associated with lower hypertension risk in Chinese (HR = 0.84) and American (HR = 0.86) cohorts aged 50 and older.Hobby engagement was associated with lower hypertension risk in Chinese (HR = 0.84) and American (HR = 0.86) cohorts aged 50 and older.