Preprints.org

Weight Regain During Continued Incretin Therapy Is Associated With an Inflammatory Signature at Weight Nadir and Higher Cardiovascular Event Rates

Preprint: cohort study of 58,618 peoplePopulations

Abstract

For patients treated with semaglutide or tirzepatide, weight-loss plateau followed by regain is a major concern, yet rebound occurring while treatment continues to be documented remains underappreciated and its biological correlates are poorly understood.

The paper