Research Square

Gut microbial arginine biosynthesis mediates the anti-obesity effect of a pasteurized Akkermansia muciniphila 11

Preprint: trial in peopleInterventions

Abstract

Background Akkermansia muciniphila is regarded as a promising next-generation probiotic for metabolic disorders, yet the postbiotic modes of action through which it exerts benefits remain poorly defined. This study explored how pasteurized A. muciniphila (pAkk11) might influence host metabolism by remodeling the gut microbial ecosystem.

The paper

Henan University of Science and Technology

Research Square, 14 Aug 2026, CC BY, Preprint, not peer-reviewed

doi.org/10.21203/rs.3.rs-9834663/v1