Frontiers in Neurology·7 OctEffects of acute sleep deprivation on individuals across different APOE genotypes: a randomized controlled trial protocolStudy protocolMechanismsPaper
Scientific Reports·7 OctLoneliness, restless sleep, and incident possible or confirmed sarcopenia among middle-aged and older Chinese adultsCohort study of 6,614 peopleMusclePaper
JACC Advances·24 SepLife-Course Noncardiac Comorbidity Burden and Mortality in Lower-Complexity Congenital Heart DiseaseCohort study of 492,232 peoplePopulationsPaper
Frontiers in Immunology·24 SepLow serum complement C3 levels are associated with all-cause mortality in Chinese centenarians: a prospective cohort studyCohort study of 906 peopleBiomarkersPaper
bioRxiv·24 SepARSA: an autonomous research scientist for target nomination in Alzheimer's disease and related dementiasPreprint: computational studyAI & dataPaper
Frontiers in Aging·23 SepMolecular markers, mechanisms and metrics of biological aging: a scoping reviewSystematic reviewBiomarkersPaper
bioRxiv·21 SepA discrete Connexin26+ neural crest lineage emerges in mid-life and mediates enhanced central brainstem responses to elevated CO2 levels for deep breathingPreprint: experiments in miceMechanismsPaper
Nature Communications·17 SepCK2α restriction of STING accumulation underlies systemic agingExperiments in miceSTING1Paper
Biology·15 SepCombined Exendin-4 and Rituximab Treatment Improves β-Cell Function and Delays Disease Progression in NOD MiceExperiments in animalsInterventionsPaper
Journal of Thoracic Disease·11 SepMortality and predictive models for 90-/180- day postoperative death for NSCLC patients aged ≥70 yearsStudy in peopleBiomarkersPaper
Frontiers in Endocrinology·8 SepSenescent immune cells, inflammaging, and bone loss: therapeutic potential and translational challenges of senolytics in osteoporosisReviewSenolyticsPaper
International Journal of Rheumatic Diseases·3 SepCross-Sectional and Longitudinal Association Between Biological Aging Acceleration and the Risk of Osteoarthritis: A Cohort Study From UK BiobankCohort study of 332,261 peoplePhenoAgePaper
The EPMA Journal·2 SepGut microbiota-bile acid axis in cardiovascular disease: a spatiotemporal framework for predictive, preventive and personalised medicineReviewMechanismsPaper
Biomaterials·1 SepAn energy-boosting hydrogel couples magnetoelectrical stimulation and metabolic support for enhanced spinal cord regenerationExperiments in animalsInterventionsPaper
Frontiers in Nutrition·1 SepCorrelation analysis between eight anthropometric indicators and arterial stiffness in relatively healthy Chinese adultsCross-sectional study of 1,425 peopleArterial stiffnessPaper
Frontiers in Neurology·1 SepDose-response and recovery trajectories of fall prevention rehabilitation in older patients with vertigo: a retrospective cohort study based on vestibular and gait impairment phenotypesCohort study of 756 peopleInterventionsPaper
Research Square·22 AugStable brain architecture but flexible dynamics: distinct structure - function coupling signatures link aging and genetic Alzheimer's risk to cognitive decline in 34,067 adultsPreprint: cohort study of 34,067 peopleMechanismsPaper
Frontiers in Cardiovascular Medicine·21 AugComparative associations and incremental predictive value of cardiometabolic and inflammatory indices for short- to mid-term cardiovascular disease risk in two Chinese cohortsCohort study of 7,170 peopleCardiovascular diseasePaper
The Journal of Nutrition, Health & Aging·18 AugMultivariable-adjusted multi-omics signatures reveal gut microbial functional alterations and metabolic dysregulation in intrinsic capacity declineCross-sectional study of 121 peopleBiomarkersPaper
Research Square·15 AugGut microbial arginine biosynthesis mediates the anti-obesity effect of a pasteurized Akkermansia muciniphila 11Preprint: trial in peopleInterventionsPaper