Research Square

Imaging-based biological age estimation predicts competing mortality risk in lung cancer screening

By Daryl Cheng, John McCabe, Tanya Patrick, Joseph Jacob

Preprint: cohort study of 12,478 peopleBiomarkers

5 years

Abstract

Background Lung cancer screening (LCS) participants have a high competing risk of non-lung cancer related death, which limits screening benefit. We hypothesized that imaging-based biological age can identify individuals at higher risk of non-lung cancer mortality.

Imaging
Deep learning
Machine learning
Imaging-based biological age
Lung cancer
Humans

The paper

University College London

Research Square, 10 Aug 2026, CC BY, Preprint, not peer-reviewed

doi.org/10.21203/rs.3.rs-9073407/v1

Imaging-based biological age estimation predicts competing mortality risk in lung cancer screening

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Imaging-based biological age estimation predicts competing mortality risk in lung cancer screening

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