Research Square

Stable redundancy and variable ranking of metabolic surrogate indicators for incident ischemic heart disease

Preprint: cohort study of 7,795 peopleBiomarkers

Independent replication

Abstract

Background Metabolic surrogate indicators built from routine lipid, glycemic, and anthropometric measurements are often used in cardiovascular risk stratification. Because many of these formulas are different arrangements of the same inputs, single-cohort rankings may overstate how much new information a formula provides.

The paper

Anhui University of Traditional Chinese Medicine

Research Square, 7 Aug 2026, CC BY, Preprint, not peer-reviewed

doi.org/10.21203/rs.3.rs-10258728/v1