Research Square
Association Between Longitudinal Change in the Cystatin C-to-HDL Cholesterol Ratio and Subsequent Heart Disease in Non-Diabetic Adults: A CHARLS Cohort Study
Preprint: cohort study of 3,133 peopleBiomarkers
Abstract
Background Cardiovascular-kidney-metabolic abnormalities may precede overt diabetes, but practical markers of longitudinal cross-system deterioration remain limited.
- Cystatin C-to-HDL cholesterol ratio
- Heart disease
- C-reactive protein
- Cardiovascular-kidney-metabolic syndrome
- eGFR
- Humans
The paper
Shantou Central Hospital
Research Square, 6 Aug 2026, CC BY, Preprint, not peer-reviewed


