Research Square

Association Between Longitudinal Change in the Cystatin C-to-HDL Cholesterol Ratio and Subsequent Heart Disease in Non-Diabetic Adults: A CHARLS Cohort Study

Preprint: cohort study of 3,133 peopleBiomarkers

Abstract

Background Cardiovascular-kidney-metabolic abnormalities may precede overt diabetes, but practical markers of longitudinal cross-system deterioration remain limited.

The paper

Shantou Central Hospital

Research Square, 6 Aug 2026, CC BY, Preprint, not peer-reviewed

doi.org/10.21203/rs.3.rs-10434846/v1