Frontiers in Cardiovascular Medicine
Development and internal-external validation of an interpretable machine learning model integrating clinical and polygenic predictors for coronary artery disease: a multicenter retrospective cohort study
Cohort study of 2,067 peopleBiomarkers
Independent replication, multicentre
- Machine learning
- Coronary artery disease
- Low-density lipoprotein cholesterol
- Polygenic risk score
- Predicted coronary artery disease risk category
- Humans
The paper
Wuxi No.2 People's Hospital
Frontiers in Cardiovascular Medicine, 24 Sep 2026
