Predicted coronary artery disease risk category

Predicted coronary artery disease risk category is associated with coronary artery disease incidence in humans (5-year cumulative incidence: 2.7%, 7.2%, and 19.8% in low-, intermediate-, and high-risk categories).

HumansPrespecified low-, intermediate-, and high-risk categories5 yearsn = 2,067

Development and internal-external validation of an interpretable machine learning model integrating clinical and polygenic predictors for coronary artery disease: a multicenter retrospective cohort study

Frontiers in cardiovascular medicine·24 Sep 2026