BiomarkersHumans3,011 community-dwelling adultsCohort study

Detailed ability checks added little to ranking death risk

After accounting for demographic and social factors and multiple illnesses, death-risk ranking scores were 0.723 for brief screening, 0.731 for comprehensive assessment and 0.736 for statistical scoring.

Figure 1 from The Journal of Nutrition, Health & Aging
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Figure 1Kim et al.

The Journal of Nutrition, Health & Aging

An observational cohort study followed 3,011 community-dwelling adults aged 70–84 in South Korea for a median of eight years. Researchers compared three measures of intrinsic capacity, a person's combined physical and mental abilities: a brief screen, a comprehensive clinical assessment and a statistically calculated score.

More detailed measures distinguished frailty, a state of increased vulnerability to health problems, better. The measures did not clearly differ in distinguishing disability in daily activities. There were 500 deaths. Higher capacity on each measure was associated with lower mortality after accounting for demographic and social factors and multiple illnesses. The adjusted models ranked long-term death risk similarly. Capacity measures alone ranked death risk less well and performed similarly to one another.

Why it matters

Older adults' physical and mental abilities underpin the World Health Organization's integrated care programme. The findings support the potential feasibility of brief screening within that approach.

Caveats

This observational study assessed associations, not whether screening or changing capacity improves outcomes. The brief screen was built to align with the statistical measure, so these findings do not validate the World Health Organization's screening instrument.

The paper

Criterion validity of brief, comprehensive, and latent measures of intrinsic capacity against frailty, disability, and mortality in older adults

Sunyoung Kim, Lan Luo, Sandra M Shi,
Show 4 more authorsChan Mi Park, Kevin T Pritchard, Miji Kim, Chang Won Won,
Dae Hyun Kim

Kyung Hee University Medical Center · Hinda and Arthur Marcus Institute for Aging Research

The Journal of Nutrition, Health & Aging · 7 Oct 2026

doi.org/10.1016/j.jnha.2026.101002PubMed 42843119