The Eukaryotic Host-Microbe-Phage-Nutrition Interplay Determines the Bacterial Effectors of Supplemental Lysine's Health Benefits: An Experimental Cellular Senescence Model of Digestive Conditions in Older Adults
Mechanisms of ageing and development · Ghadimi D et al. · Paper published 26 Sep 2026
We haven’t written this paper up. Its abstract belongs to the publisher, so read it at the source.
The paper
The Eukaryotic Host-Microbe-Phage-Nutrition Interplay Determines the Bacterial Effectors of Supplemental Lysine's Health Benefits: An Experimental Cellular Senescence Model of Digestive Conditions in Older Adults
Ghadimi D, Blömer S, Kaya AŞ et al.
Mechanisms of ageing and development · 26 Sep 2026 · Peer-reviewed
- Relevance
- Relevant
- News value
- Notable
- Evidence
- Cells
- Status
- Peer-reviewed
More on Cellular senescence
See allDasatinib and quercetin reduce liver fibrosis in a phase-2 MASH trial
The senolytic combination improved liver fibrosis without disease worsening in nearly half of treated participants while lowering cellular senescence markers.
Nature metabolism · Koning M et al.
A distinct p21-driven macrophage senotype accumulates during aging and liver disease
Researchers identified a p53-p21-Cyclin D2 axis that governs senescent macrophages in mice and human liver cirrhosis and can be cleared with senolytics.
bioRxiv · Torres G et al.
DNA methylation proxies of senescence markers track human disease and mortality
The new blood-based tools estimate senescence gene activity to predict incident diseases, all-cause mortality, and clinical treatment responses.
medRxiv · Simpson DJ et al.
Bispecific T cell engager eliminates senescent cells in mice and nonhuman primates
Monitored by serum transaminase levels, low doses of the drug alleviated age-related pathologies without causing the hepatotoxicity seen at higher doses.
Aging cell · Deng J et al.
A deep learning score for cellular senescence predicts human mortality and disease risk
The proteomic biomarker tracked chronic illness risk in the UK Biobank and shifted following an 18-month multimodal exercise intervention.
Aging cell · Zhao S et al.