International Journal of Molecular Sciences
Sleep Disturbance Correlates with Cognitive Impairment Partly via Plasma p-Tau217: ADNI Cross-Sectional Evidence and P301L Mouse Mechanistic Observations
Cross-sectional study of 230 peopleMechanisms
Abstract
How sleep disturbances link to cognitive decline in Alzheimer's disease (AD) via tau pathology is unclear. We explored whether sleep dysfunction worsens cognitive deficits by elevating plasma phosphorylated tau217 (p-Tau217).
The paper
Huazhong University of Science and Technology
International Journal of Molecular Sciences, 17 Sep 2026, CC BY
