Integrative Identification of Candidate Protein Targets and Compounds for Dystonia Using Mendelian Randomization, Single-Cell RNA Sequencing, and Network Pharmacology

Genes

Abstract

Background Dystonia is a severe neurological disorder with enigmatic pathogenesis. Current treatment options are limited in preventing the disease progression, underscoring the urgent need for new targeted therapeutic agents to develop more effective therapies.

The paper

Lin Chen, Ming-juan Fang, Nan Cheng, Yin Xu

Anhui University of Traditional Chinese Medicine

Genes · 3 Sep 2026 · CC BY

doi.org/10.3390/genes17091067PubMed 42792961