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InterventionsHuman trial24 months·Randomised trial

Semaglutide and cardiovascular risk reduction: a mediation analysis of the SELECT trial

European Heart Journal

  • Semaglutide
  • Causal inference
  • GLP-1 and incretin signalling
  • Cardiovascular disease
  • All potential mediators investigated
  • Humans

The paper

Colhoun HM, Lincoff AM, Ryan D et al.

European Heart Journal · 23 Sep 2026

doi.org/10.1093/eurheartj/ehag524PubMed 42777687

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