Translational Psychiatry
Regional juxtacortical microstructural changes and gene expression provide insights into neurodegeneration in Alzheimer's disease
Study in peopleMechanisms
The paper
Junfang Zhang, Lipeng Sun, Xinyuan Yang, +464Show 464 more authors, Lin Kang, Yingting Zheng, Qi Huang, Wei Xu, Yihui Guan, Jun Liu, Yulei Deng, Fang Xie, Xiaomeng Xu, Binyin Li, for the Alzheimer’s Disease Neuroimaging Initiative, Michael Walter Weiner, Paul Aisen, Ronald Carl Petersen, Clifford R. Jack, William J. Jagust, John Q. Trojanowki, Arthur W. Toga, Laurel A. Beckett, Robert C. Green, Andrew J. Saykin, John C. Morris, Richard J. Perrin, Leslie M. Shaw, Maria C. Carrillo, William Potter, Lisa Laverne Barnes, Marie Bernard, Hector González, Carole Ho, John K. Hsiao, Jonathan Jackson, Eliezer Masliah, Donna M. Masterman, Ozioma Okonkwo, Richard Perrin, Laurie M. Ryan, Nina B. Silverberg, Adam Fleisher, Juliet Fockler, Cat Conti, Dallas P. Veitch, John Neuhaus, Chengshi Jin, Rachel Nosheny, Miriam T. Ashford, Derek Flenniken, Adrienne Kormos, Gustavo Jiménez, Michael Donohue, Devon Gessert, Jennifer Salazar, Caileigh Zimmerman, Yuliana Cabrera, Sarah Walter, Garrett Miller, Godfrey Coker, Taylor Clanton, Lindsey Hergesheimer, Stephanie Smith, Olusegun Adegoke, Payam Mahboubi, Shelley Moore, Jeremy Pizzola, Elizabeth Shaffer, Brittany Sloan, Danielle J. Harvey, Bret Borowski, Chad Ward, Christopher Schwarz, David Jones, Jeff L. Gunter, Kejal Kantarci, Matthew Senjem, Prashanthi Vemuri, Robert Reid, Nick C. Fox, Ian Malone, Paul Thompson, Sophia I. Thomopoulos, Talia M. Nir, Neda Jahanshad, Charles S DeCarli, Alexander Knaack, Evan Fletcher, Duygu Tosun, Stephanie Rossi Chen, Mark Choe, Karen L. Crawford, Paul A. Yushkevich, Sandhitsu Das, Robert A. Koeppe, Eric M. Reiman, Kewei Chen, Chet Mathis, Susan Landau, Richard Perrin, Nigel J. Cairns, Erin Householder, Erin Franklin, Haley Bernhardt, Lisa Taylor-Reinwald, Leslie M. Shaw, John Q. Trojanowki, Magdalena Korecka, Michal Figurski, Karen L. Crawford, Scott Neu, Andrew J. Saykin, Kwangsik Nho, Shannon L. Risacher, Liana G. Apostolova, Li Shen, Tatiana M. Foroud, Kelly Nicole Holohan Nudelman, Kelley M. Faber, Kristi Wilmes, Leon J. Thal, Zaven S. Khachaturian, John K. Hsiao, Lisa C. Silbert, Betty Lind, Rachel Crissey, Jeffrey Alan Kaye, Raina Carter, Sara Dolen, Joseph Quinn, Lon S. Schneider, Sonia Pawluczyk, Mauricio Becerra, Liberty Teodoro, Karen Dagerman, Bryan M. Spann, James Brewer, Helen Vanderswag, Adam Fleisher, Jaimie Ziolkowski, Judith L. Heidebrink, Lisa Zbizek-Nulph, Joanne L. Lord, Colleen S. Albers, David S. Knopman, Kris Johnson, Javier Villanueva-Meyer, Valory Pavlik, Nathaniel Pacini, Ashley Lamb, Joseph S. Kass, Rachelle S. Doody, Victoria Shibley, Munir Chowdhury, Susan Rountree, Mimi Dang, Yaakov Stern, Lawrence S. Honig, Akiva Mintz, Beau Ances, David Winkfield, Maria Carroll, Georgia Stobbs-Cucchi, Angela Oliver, Mary L. Creech, Mark A. Mintun, Stacy Schneider, David Geldmacher, Marissa Natelson Love, Randall Griffith, David Clark, John Brockington, Daniel Marson, Hillel T. Grossman, Martin A. Goldstein, Jonathan Greenberg, Effie Mitsis, Raj C. Shah, Melissa Lamar, Patricia Samuels, Ranjan Duara, Maria T. Greig-Custo, Rosemarie Rodriguez, Marilyn S. Albert, Chiadi Onyike, Leonie Farrington, Scott Rudow, Rottislav Brichko, Stephanie Kielb, Amanda Smith, Balebail Ashok Raj, Kristin Fargher, Martin Sadowski, Thomas Wısnıewskı, Melanie B. Shulman, Arline Faustin, Julia Rao, Karen M. Castro, Anaztasia Ulysse, Shannon Chen, Mohammed O. Sheikh, Jamika Singleton-Garvin, Doraiswamy Pm, Jeffrey R. Petrella, Olga G James, Terence Z. Wong, Salvador Borges-Neto, Jason H. Karlawish, David A. Wolk, Sanjeev Vaishnavi, Christopher M. Clark, Steven E. Arnold, Charles D. Smith, Gregory A. Jicha, Riham El Khouli, Flavius D. Raslau, Oscar L. López, MaryAnn Oakley, Donna M. Simpson, Anton P. Porsteinsson, Kim Martin, Nancy Kowalski, Melanie Keltz, Bonnie S. Goldstein, Kelly M. Makino, M. Saleem Ismail, Connie Brand, Gaby Thai, Aimee Pierce, Beatriz Yanez, Elizabeth Sosa, Megan Witbracht, Brendan J. Kelley, Trung Nguyen, Kyle B. Womack, Dana Mathews, Mary Ellen Quiceno, Allan I. Levey, James J. Lah, Ihab Hajjar, Janet S. Cellar, Jeffrey Murray Burns, Russell Howard Swerdlow, William M. Brooks, Daniel H.S. Silverman, Sarah Kremen, Liana Apostolova, Kathleen Tingus, Po H. Lu, George Bartzokis, Ellen Woo, Edmond Teng, Neill R. Graff-Radford, Francine C. Parfitt, Kim Poki-Walker, Martin R. Farlow, Ann Marie Hake, Brandy R. Matthews, Jared R. Brosch, Scott Herring, Christopher H. van Dyck, Adam P. Mecca, Susan P. Good, Martha G. MacAvoy, Richard E. Carson, Pradeep Varma, Howard Mark Chertkow, Susan Vaitekunis, Chris Hosein, Sandra Black, Bojana Stefanovic, Chris Chinthaka Heyn, Ging-Yuek Robin Hsiung, Ellen Kim, Benita Mudge, Vesna Sossi, Howard Feldman, Michele Assaly, Elizabeth Finger, Stephen Pasternak, Irina Rachinsky, Andrew Kertesz, Dick Drost, John Rogers, Ian Grant, Brittanie Muse, Emily J. Rogalski, Jordan Robson, M.-Marsel Mesulam, Diana Kerwin, Chuang-Kuo Wu, Nancy Johnson, Kristine Lipowski, Sandra Weıntraub, Borna Bonakdarpour, Nunzio Pomara, Raymundo T. Hernando, Antero Sarrael, Howard J. Rosen, Bruce L. Miller, David C. Perry, Raymond Scott Turner, Kathleen B. Johnson, Brigid Reynolds, Kelly McCann, Jessica Poe, Reisa Anne Sperling, Keith A. Johnson, Gad A. Marshall, Christine M. Belden, Alireza Atri, Bryan M. Spann, Kelly A. Clark, Edward Zamrini, Marwan Sabbagh, Ronald Killiany, Robert Stern, Jesse Mez, Neil Kowall, Andrew E. Budson, Thomas Olabode Obisesan, Oyonumo E. Ntekim, Saba Wolday, Javed I. Khan, Evaristus A. Nwulia, Sheeba Nadarajah, Alan Lerner, Paula Ogrocki, Curtis Tatsuoka, Parianne Fatica, Evan Fletcher, Pauline Maillard, John Olichney, Charles S DeCarli, Owen Carmichael, Vernice E. Bates, Horacio Capote, Michelle M. Rainka, Michael Borrie, T-Y Lee, Rob Bartha, Sterling C. Johnson, Sanjay Asthana, Cynthia M. Carlsson, Allison Perrin, Anna Burke, Douglas W. Scharre, Maria Kataki, Rawan M. Tarawneh, Brendan J. Kelley, David Hart, Earl A. Zimmerman, Dzintra F. Celmins, Delwyn D. Miller, Laura L. Boles Ponto, Karen Ekstam Smith, Hristina K. Koleva, Hyungsub Shim, Ki Won Nam, Susan K. Schultz, Jeff D. Williamson, Suzanne Craft, Jo Cleveland, Mia Yang, Kaycee M. Sink, Brian R. Ott, Jonathan D. Drake, Geoffrey Tremont, Lori A. Daiello, Jonathan D. Drake, Marwan Sabbagh, Aaron Ritter, Charles Bernick, Donna Munic, Akiva Mintz, Abigail O’Connelll, Jacobo E Mintzer, Arthur Wiliams, Joseph Masdeu, Jiong Shi, Angelica Garcia, Marwan Sabbagh, Paul Newhouse, Steven Potkin, Stephen Salloway, Paul Malloy, Stephen Correia, Smita Kittur, Godfrey D. Pearlson, Karen Blank, Karen Anderson, Laura A. Flashman, Marc A. Seltzer, Mary L. Hynes, Robert B. Santulli, Norman R. Relkin, Gloria Chiang, Michael Lin, Lisa Ravdin, Athena Lee, Ron Petersen, Thomas Neylan, Jordan Henry Grafman, Tom Montine, Sarah Danowski, Catherine Nguyen-Barrera, Shannon Finley, Danielle J. Harvey, Michael Donohue, Matthew Bernstein, Norm Foster, Tatiana M. Foroud, Steven Potkin, Li Shen, Kelley M. Faber, Sungeun Kim, Kwangsik Nho, Kristi Wilmes, Helen Vanderswag, Adam Fleisher, Ajay Sood, Kimberly S. Blanchard, Debra A. Fleischman, Maria T. Greig, Bonnie Goldstein, Kimberly S. Martin, Gaby Thai, Aimee Pierce, Christopher Reist, Beatriz Yanez, Elizabeth Sosa, Megan Witbracht, Carl Sadowsky, Walter Martinez, Teresa Villena, Howard H. Rosen, Elaine R. Peskind, Eric C. Petrie, Gail Li, Jerome Albert Yesavage, Joy L. Taylor, Steven Z. Chao, Jaila Coleman, Jessica D. White, Barton Lane, Allyson Rosen, J. R. Tinklenberg, Gustavo Adolfo Jimenez-Maggiora, Erin Drake, Mike Donohue, Craig J. Nelson, David D. Bickford, Meryl Butters, Michelle D. Zmuda, Bret Borowski, Jeff L. Gunter, Matt Senjem, Kejal Kantarci, Chad Ward, Denise Reyes, Kelley M. Faber, Kelly Nicole Holohan Nudelman, Yiu Ho Au, Kelly Scherer, Daniel Catalinotto, Samuel Stark, Elise Ong, Dariella Fernandez
Shanghai Jiao Tong University; University of California, San Francisco
Translational Psychiatry, 30 Jul 2026
