Papers by Richard J. Perrin · AgingResearch.News

medRxiv1 Oct
Gantenerumab reduces brain amyloid-β proteoforms: Biochemical evaluation in dominantly inherited Alzheimer disease
Preprint: non-randomised trial in peopleAlzheimer's disease
Paper
PsyArXiv25 Sep
Remote Digital Cognitive Assessment in a Trial-Ready Alzheimer’s Cohort: A Scalable Approach for Early Intervention Studies
Preprint: cohort study of 162 peopleAlzheimer's disease
Paper
Translational Psychiatry16 Sep
Regional juxtacortical microstructural changes and gene expression provide insights into neurodegeneration in Alzheimer's disease
Study in peopleMechanisms
Paper
Alzheimer's & Dementia10 Sep
Remote digital cognitive assessment in a trial-ready Alzheimer's disease cohort: A scalable approach for early intervention studies
Cohort study of 123 peopleAlzheimer's disease
Paper

AAIC 2025 Abstract10 Jan
Elevated CSF levels of matrix metalloproteinase‐12 as a potential marker for microhemorrhage risk in autosomal dominant Alzheimer disease
Study in peopleBiomarkers
Paper
AAIC 2025 Abstract10 Jan
Imaging‐neuropathology evaluation of Amyloid Related Imaging Abnormality sulcal effusion in a DIAN‐TU‐001 participant treated with gantenerumab
Trial in peopleInterventions
Paper
AAIC 2025 Abstract7 Jan
Aβ positive, tau biomarker negative cognitive impairment is associated with significant non‐Alzheimer's disease neuropathologies
Study in peopleBiomarkers
Paper
AAIC 2025 Abstract26 Dec
Early Detection and Monitoring of Amyloid‐Related Imaging Abnormalities in Monoclonal Antibody Therapy Using Generalized Diffusion Basis Spectrum Imaging (g‐DBSI): A Pilot Study
Trial in peopleBiomarkers
Paper
AAIC 2025 Abstract25 Dec
Novel early‐onset Alzheimer‐associated genes influence risk through dysregulation of glutamate, immune activation, and intracell signaling pathways
Study in peopleMechanisms
Paper
AAIC 2025 Abstract24 Dec
Age‐ and sex‐effects on tau PET binding in the absence of beta‐amyloid pathology
Study in peopleMechanisms
Paper
AAIC 2025 Abstract23 Dec
Imaging‐neuropathology evaluation of Amyloid Related Imaging Abnormality sulcal effusion in a DIAN‐TU‐001 participant treated with gantenerumab
Trial in peopleInterventions
Paper
AAIC 2025 Abstract23 Dec
Elevated CSF levels of matrix metalloproteinase‐12 as a potential marker for microhemorrhage risk in autosomal dominant Alzheimer disease
Study in peopleBiomarkers
Paper
AAIC 2025 Abstract23 Dec
Early Detection and Monitoring of Amyloid‐Related Imaging Abnormalities in Monoclonal Antibody Therapy Using Generalized Diffusion Basis Spectrum Imaging (g‐DBSI): A Pilot Study
Trial in peopleBiomarkers
Paper