Skip to content
AgingResearch.News
  • HomeHome
  • SearchSearch
  • AskAsk
  • FollowingFollowing
  • SavedSaved
AgingResearch.News
International Urogynecology Journal

Thrombospondin-1 as a Mechanosensitive Matrix Protein Driving Fibroblast Senescence: A Novel Pathogenic Target for Pelvic Organ Prolapse

By Yaqin Li, Fuqing Feng, Yue Zhang, +2Show 2 more authors, Xiuli Sun
Experiments in cellsMechanisms
Paper

The paper

Yaqin Li, Fuqing Feng, Yue Zhang, +2Show 2 more authors, Shujia Xu, Bing Xie, Xiuli Sun

Peking University

International Urogynecology Journal, 14 Sep 2026

doi.org/10.1007/s00192-026-06878-zPubMed 42734638

Related

  • bioRxiv·2 Oct 2026

    Ovarian stiffness increases with age and tracks with declining egg yield

  • EMBO Molecular Medicine·3 Oct 2026

    Prostaglandin E2 drives cellular senescence and scar fibrosis after cesarean section in mice

  • bioRxiv·8 Oct 2026

    Human ovaries show age-linked protein shifts after menopause

  • Neoplasia·2 Oct 2026

    Senescent prostate cancer cells drive stromal remodeling through TGF-beta signaling

PrivacyTermsContact© 2026 AgingResearch.News

    News

    See all
    ER-100 glaucoma trial findings support testing higher dosesTrialsLongevity.Technology and 3 moreNew immune cell map reveals how individual immune aging trajectories divergeResearchMedical Xpress and 2 moreNewer cohorts of older Europeans show slower intrinsic capacity lossResearchThe Lancet Healthy Longevity

    Trials

    See all
    AKG and Brain Health in AgingPhase 2Registered 6 Oct 2026, University of OklahomaSafety and Preliminary Efficacy of Adipose-Derived Stem Cell Secretome in Frailty (VinVital)Phase 1Registered 2 Oct 2026, Vinmec Research Institute of Stem Cell and Gene TechnologyAI-Based Conversational Social Support for Older Adults With Heart FailureRegistered 7 Oct 2026, Chang Gung University of Science and Technology

    Trending

    See all
    Vitamin D deficiencyDiseaseSevere vitamin D deficiency is linked to higher death rates, and 1 more story this weekKetogenic dietInterventionKetogenic diet improved heart function in aged miceNicotinamide ribosideInterventionNicotinamide riboside did not improve early Parkinson diseaseTERTGeneBlood-cell telomerase delays premature aging in zebrafishPregnancyInterventionEstimated brain-age gap rises by three years in pregnancyChildhood lonelinessInterventionChildhood loneliness linked to faster frailty progression

    Topics

    See all
    Mechanisms249Interventions422Biomarkers402Populations534AI & data162Industry & policy16
    • Privacy
    • Terms
    • Contact
    • © 2026 AgingResearch.News