Experimental & Molecular Medicine

TRANsCre-DIONE transdifferentiates scar-forming reactive astrocytes into functional motor neurons

By Heeyoung An, Hye-Lan Lee, Doo-Wan Cho, Changjoon Justin Lee

Experiments in animalsInterventions

The paper

Heeyoung An, Hye-Lan Lee, Doo-Wan Cho, Changjoon Justin Lee

Institute for Basic Science

Experimental & Molecular Medicine, 11 Sep 2026

doi.org/10.1038/s12276-026-01815-y PubMed 42722703

Neurobiology of Disease10 Oct 2026
Reprogrammed human neurons survive and mature in mice
bioRxiv2 Oct 2026
Astrocytic secretome enhances hippocampal neurogenesis and spatial memory in mice
Cell Reports6 Oct 2026
A protein helps zebrafish repair spinal cords without lasting scars
Glia3 Oct 2026
Astrocyte subsets in the hippocampus age differently