Experimental Gerontology

Integrated transcriptomic and proteomic analysis reveals ECM disruption and ALDH1L1-linked metabolic remodeling in klotho-deficient post-infarction heart failure

By Bing Zhao, Chun Xiao

Experiments in animalsMechanisms

The paper

Bing Zhao, Chun Xiao

Guangzhou Medical University

Experimental Gerontology, 31 Aug 2026

doi.org/10.1016/j.exger.2026.113307 PubMed 42674223

American Journal of Physiology Heart and Circulatory Physiology3 Oct 2026
Mitochondrial proteostasis is impaired in mouse heart failure
European Journal of Heart Failure2 Oct 2026
Proteomic multi-organ aging accelerates before adverse events in heart failure patients
Acta Physiologica5 Oct 2026
Klotho deficiency disrupts potassium balance in mice
Experimental Gerontology8 Oct 2026
Ketogenic diet improved heart function in aged mice