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Mutation-resolved single-cell transcriptomics reveals enhanced β-amyloid clearance in TET2-mutant human monocytes

By Xiao Yang, Sameen Fatima, Salvador Sampere-Birlanga, Show 10 more authorsWesley Tyler Abplanalp
Figure 1. TET2-mutant carriers and cells exhibit enhanced phagocytic signatures in aged individuals.
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Figure 1. TET2-mutant carriers and cells exhibit enhanced phagocytic signatures in aged individuals.TET2-mutant carriers and cells exhibit enhanced phagocytic signatures in aged individuals.Yang et al.
Experiments in human cellsMechanisms
Paper

The paper

Xiao Yang, Sameen Fatima, Salvador Sampere-Birlanga, Show 10 more authorsWesley Tyler Abplanalp

Goethe University Frankfurt

JCI Insight, 24 Aug 2026

doi.org/10.1172/jci.insight.208804PubMed 42635046

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