PopulationsHumans6,330 participants7 yearsCohort study

Living conditions linked to multiple heart or metabolic diseases

The low-risk living-environment group had a lower rate of new cases than the high-risk group, with a hazard ratio, comparing these rates, of 0.51.

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Figure 1Chen et al. · CC BY

BMC Public Health

An observational cohort study followed 6,330 adults aged 45 or older in China who initially did not have cardiometabolic multimorbidity: multiple conditions affecting the heart, blood vessels or how the body uses energy. Researchers built an index of living environmental quality. They compared groups after accounting for differences in participants’ backgrounds, behaviours and health.

Over seven years, 482 participants developed these coexisting conditions. More favourable residential environments were associated with lower risk. The middle-risk environmental group had a hazard ratio of 0.78 compared with the high-risk group. Living in a multi-storey building and access to tap water were each associated with lower risk. The overall association remained generally consistent across analyses that tested the robustness of the results.

Why it matters

Coexisting heart and metabolic conditions are a growing concern in aging populations. Considering several residential features together may help researchers understand the role of people’s surroundings in health in later life.

Caveats

This observational study cannot show that living conditions caused the differences in risk. Other factors may still have influenced the associations, and the environmental-quality index had limitations.

The paper

Living environmental quality and incident cardiometabolic multimorbidity: a prospective cohort study in China

Chen H, Yue S, Hou S et al.

BMC Public Health · 6 Oct 2026 · CC BY

doi.org/10.1186/s12889-026-29751-6