Obstetrical & Gynecological Survey

Timed eating helped women with polycystic ovary syndrome lose weight

In a six-month randomized trial of 76 women, eating within six hours reduced weight versus controls but did not significantly outperform daily calorie restriction.

Paper by David L. Keefe · UMass Memorial Health Care
Fat tissue with large cells sits between two patches of smaller cells, each beside a plate with different portions of grains and leaves.
Studied:
Randomized trial in 76 women with polycystic ovary syndrome, against nonintervention controls
What changed:
Body weight fell with timed eating compared with controls
The catch:
The six-month trial did not assess longer-term weight control
In the record:
The 636th paper on caloric restriction with results in people; 4,186 on record in all. Its result on body weight agrees with 322 of 332 other findings on record; 1 points the other way and 9 found no change.
Why it’s aging research:
It studies an intervention with evidence of extending healthy life.

Editor of record: Boris Djordjevic · AgingResearch.News

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Seventy-six women with polycystic ovary syndrome, a hormonal condition that can disrupt ovulation, took part in a six-month randomized trial summarized in a commentary. One group ate only between 1 p.m. and 7 p.m. Another cut daily calorie intake by 25%. Controls ate over at least 10 hours each day.

Both eating plans reduced body weight, fat mass and waist size compared with controls. The trial found no significant differences between the two plans for these outcomes. Neither plan significantly changed menstrual regularity or other symptoms of the condition. Women assigned to the six-hour eating window reported following it on 80% of days. The analysis included all 76 participants.

Why it matters

Polycystic ovary syndrome affects reproductive-age women and can involve insulin resistance, when the body responds poorly to insulin. Weight management offers one approach to managing the condition’s metabolic and reproductive effects.

Caveats

The six-month trial did not assess longer-term weight control or results in women without polycystic ovary syndrome. The commentary’s abstract gives no weight-loss amounts or adverse-event results, limiting assessment of benefit size and harms.

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