MechanismsCells94 individualsCohort study

The Role of Senescence-Associated Interferon in Age-Related Inflammation

GSA 2025 Abstract

Abstract

Inflammaging, age-related deterioration of immune function, features persistent inflammation alongside an exacerbated immune response to pathogens. Senescent monocytes accumulate with age and release harmful proteins, potentially driving hyperinflammation.

The paper

Shrivastava M, Banarjee R, Olinger B et al.

GSA 2025 Abstract · 31 Dec 2025 · CC BY

Presented at GSA 2025

doi.org/10.1093/geroni/igaf122.3332