Bathtub Curve Patterns of Mortality Risk in Cardiometabolic Diseases: A Cohort Study Using the UK Biobank

Abstract

Observational studies suggest nonlinear mortality patterns in cardiometabolic diseases (CMDs): acute events show early risk spikes, while chronic conditions exhibit gradual risk accumulation. These trends superficially align with the bathtub curve—an engineering model describing triphasic failure rates.

The paper