MULTI-OMIC DISSECTION OF ALZHEIMER’S DISEASE: DISENTANGLING AGING TRAJECTORIES, NEURODEGENERATION AND PATHOPHYSIOLOGICAL CONFOUNDERS

Abstract

Alzheimer’s disease (AD) is a heterogeneous, age-related neurodegenerative condition in which genetic risk, exposome, and disease biology interact in complex and non-linear ways. Multi-omic technologies now allow us to dissect this complexity at scale.