Unhealthy sleep and obesity linked to multiple chronic diseases
UK Biobank participants with unhealthy sleep and abdominal obesity had 2.55 times the rate of developing multiple heart and metabolic conditions compared with those with neither.
Our read
Populations- Studied:
- Cohort study of 362,474 UK Biobank participants, against people with neither exposure
- What changed:
- People with unhealthy sleep and abdominal obesity developed multiple heart and metabolic conditions at 2.55 times the rate of those with neither
- The catch:
- In Fuqing, disease could precede unhealthy sleep and obesity because all were measured together
- In the record:
- The 33rd paper on insomnia with results in people; 50 on record in all.
- Why it’s aging research:
- It measures an outcome that worsens with age.
Editor of record: Boris Djordjevic · AgingResearch.News
UK Biobank participants—362,474 people—were followed for a median 12.3 years in a prospective observational study. During follow-up, 3,980 developed at least two of type 2 diabetes, coronary heart disease and stroke. A separate cross-sectional analysis examined 34,703 Fuqing Cohort participants.
Unhealthy sleep meant at least three of five traits: late sleep timing, sleeping under seven or over eight hours daily, frequent insomnia symptoms, snoring and frequent daytime sleepiness. In both cohorts, unhealthy sleep combined with obesity measured by waist size had a stronger association with multiple diseases than unhealthy sleep combined with general overweight or obesity. Among Europeans, the joint association exceeded the sum of the separate associations, more strongly for abdominal obesity. A similar pattern in Asians was no longer statistically significant after adjustment for other factors.
Why it matters
Heart disease, stroke and type 2 diabetes are important concerns in later life. The authors called for public health strategies that address sleep and weight together.
Caveats
The Fuqing analysis measured sleep, obesity and disease at the same time, so it could not establish which came first. Other health or lifestyle differences could have contributed to the UK associations.
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