BiomarkersHumans
Study of brain perfusion in adults with Down Syndrome along the Alzheimer’s Disease continuum
AAIC 2025 Abstract
Abstract
Background: Down Syndrome (DS) represents a high‐risk group for Alzheimer’s disease (AD) due to chromosome 21 triplication, which drives amyloid precursor protein overproduction. While brain atrophy in DS has been widely studied, the underlying brain perfusion changes remain poorly understood.
The paper
María Franquesa‐Mullerat, Alejandra Omaira Morcillo-Nieto, José Enrique Arriola‐Infante, Alexandre Bejanin
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Sara Erzsebet Zsadanyi, Lídia Vaqué‐Alcázar, Mateus Rozalem Aranha, Javier Arranz, Íñigo Rodríguez‐Baz, Lucía Maure‐Blesa, Laura Videla, Isabel Barroeta, Laura Del Hoyo, Bessy Benejam, Susana Fernández, Aida Sanjuan Hernandez, Sandra Giménez, Daniel Andres Alcolea, Alberto Lleó, María Carmona‐Iragui, Juan Fortea,Universitat Autònoma de Barcelona
AAIC 2025 Abstract · 23 Dec 2025 · CC BY
Presented at AAIC 2025
