Early Detection and Monitoring of Amyloid‐Related Imaging Abnormalities in Monoclonal Antibody Therapy Using Generalized Diffusion Basis Spectrum Imaging (g‐DBSI): A Pilot Study

Abstract

Background: Amyloid‐Related Imaging Abnormalities (ARIA), characterized by vasogenic edema or sulcal effusions (ARIA‐E) or hemorrhagic lesions (microhemorrhages, superficial siderosis, or, rarely, microhemorrhages) (ARIA‐H), remain a significant challenge in monoclonal antibody (mAb) therapy for AD (1).

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