Associations between white matter hyperintensities (WMH), relative cerebral blood flow (rCBF), and cognition using multi‐delay ASL

Abstract

Background: White matter hyperintensity (WMH) burden has been associated with cognitive impairment, increased risk of stroke, and increased risk of dementia (DeCarli, 1995; Wardlaw, 2015). Additionally, lower cerebral blood flow (CBF) has been associated with cognitive impairment and cerebrovascular damage (Soman, 2021).