AAIC 2025 Abstract

Valiltramiprosate/ALZ‐801 Prevents Hippocampal Atrophy and Clinical Decline in a Stage 2 AD Subpopulation in APOLLOE4 Phase 3 Study

Trial in peopleInterventions

Abstract

Background: The central hallmark of Alzheimer's disease (AD) is progressive brain atrophy accompanied by amyloid and tau pathologies. Valiltramiprosate is an oral, small‐molecule inhibitor of amyloid oligomer formation in development as a disease‐modifying treatment for AD.

The paper