Microglial proteomic signature in human CSF allows stratification by APOE genotypes and is replicated in iPSC‐based model

Abstract

Background: Amyloid‐beta (Aβ) and tau proteins have been historically used as hallmark of Alzheimer’s Disease pathology. Recently, High‐throughput proteomic platforms have been implemented to support better characterization of AD patients, for the discovery of novel biomarkers and to better understand disease biology and progression.

The paper