Genetic Variation of Aquaporin‐4 Associates with Cognition, Brain Volume, and Dementia Risk in a Large Community Cohort

AAIC 2025 Abstract

Abstract

Background: The aquaporin‐4 (AQP4) water channel plays an integral role in removing waste from the brain, including β‐amyloid and tau proteins. Currently, little is known about whether genetic differences in the AQP4 gene are involved in the development of dementia.

The paper