MechanismsHumans
Genetic Variation of Aquaporin‐4 Associates with Cognition, Brain Volume, and Dementia Risk in a Large Community Cohort
AAIC 2025 Abstract
Abstract
Background: The aquaporin‐4 (AQP4) water channel plays an integral role in removing waste from the brain, including β‐amyloid and tau proteins. Currently, little is known about whether genetic differences in the AQP4 gene are involved in the development of dementia.
The paper
Emma Louise Palatsides, Dibya Himali, Stephanie R Yiallourou, Matthew Paul Pase
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Andrée‐Ann Baril, Qiong Yang, Charles S DeCarli, Alexa S. Beiser, Sudha S. Seshadri, Marina G. Cavuoto, Jayandra Jung Himali,Monash University
AAIC 2025 Abstract · 23 Dec 2025 · CC BY
Presented at AAIC 2025



