The many menopauses: Subjective Cognitive Decline in younger women with bilateral oophorectomy

Abstract

Background: There are many menopauses varying in their trajectories toward aging and some, dementia. Surgical menopause from early‐life bilateral ovarian removal (BSO), marked by immediate cessation of ovarian hormone production, notably 17‐b‐estradiol (E2), has perhaps the most severe trajectory.