AAIC 2025 Abstract

Clinical associations of CSF TMEM106B in familial and sporadic frontotemporal lobar degeneration

Study in peopleBiomarkers

Abstract

Background: TMEM106B encodes a lysosomal protein and is a genetic susceptibility factor for frontotemporal lobar degeneration (FTLD). Aptamer‐based proteomics quantifies TMEM106B protein levels in CSF.

The paper