AAIC 2025 Abstract

Impaired Brain to Nasal Turbinates Pathway in Aging Amyloid Positive Subjects Using [1‐11C]‐Butanol PET Imaging

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Abstract

Background: Reduced cerebrospinal fluid (CSF) clearance is a suggested pathological feature of Alzheimer's disease (AD). There is increasing evidence from non‐human studies that the nasal mucosa may serve as a CSF drainage site, particularly through the cribriform plate into the nose.

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