AAIC 2025 Abstract

Quantification of Amyloid and Tau associations in the Piriform Cortex in Alzheimer's and Parkinson's Disease using PET‐MR

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Abstract

Background: Olfactory‐associated regions, particularly the piriform cortex, may harbor early pathological changes in Alzheimer's (AD) and Parkinson's disease (PD). Amyloid–tau overlap is strongest in the medial temporal lobe. Amyloid–tau association in the piriform cortex versus other medial temporal structures remains unclear.

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