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Zileuton

Intervention

1 paper2 findings

MeSH

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: Korea Institute of Radiological and Medical Sciences and 1 more
  • Animals1

Outcomes

2

Senescence-associated secretory phenotype (SASP)

downin Rodentia1

1 study

  1. Zileuton inhibits senescence-associated secretory phenotype (SASP) in Rodentia.

    “treatment with zileuton inhibited SASP and mitigated radiation ulcers in animal models”

    Animalsirradiated dermal fibroblasts and skin tissue

    Zileuton Alleviates Radiation-Induced Cutaneous Ulcers via Inhibition of Senescence-Associated Secretory Phenotype in Rodents

    International journal of molecular sciencesJul 29, 2022

More on Senescence-associated secretory phenotype (SASP)

Radiation-induced cutaneous ulcer

downin Rodentia1

1 study

  1. Zileuton protects against radiation-induced cutaneous ulcer in Rodentia.

    “inhibition of 5-LO following treatment with zileuton inhibited SASP and mitigated radiation ulcers in animal models”

    Animalsradiation-induced cutaneous ulcer

    Zileuton Alleviates Radiation-Induced Cutaneous Ulcers via Inhibition of Senescence-Associated Secretory Phenotype in Rodents

    International journal of molecular sciencesJul 29, 2022

More on Radiation-induced cutaneous ulcer

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