Young ovarian tissue transplantation

Young ovarian tissue transplantation has been studied in 1 paper since 2022: none in people yet, 1 in animals. The research so far is in animals. The newest paper, Mar 29, 2022: “Aging-associated changes in motor function are ovarian somatic tissue-dependent, but germ cell and estradiol independent in post-reproductive female mice exposed to young ovarian tissue”.

Intervention

1 paper studies it3 findingsUpdated

  • 1 lab in 1 country
  • Funders: Agricultural Research Service and 3 more
  • Animals1

What did studies of Young ovarian tissue transplantation find?

3

Studies of Young ovarian tissue transplantation measured 3 outcomes; the most studied are estradiol (1 study), grip strength (1) and tremor amplitude (1).

Estradiol

no changein mice1

1 study
  1. Young ovarian tissue transplantation has no effect on estradiol in mice.

    “Estradiol levels did not change with exposure to young ovarian tissues/cells.”

    Animalsfemales

    Aging-associated changes in motor function are ovarian somatic tissue-dependent, but germ cell and estradiol independent in post-reproductive female mice exposed to young ovarian tissue

    GeroScience

More on Estradiol

Grip strength

upin mice1

1 study
  1. Young ovarian tissue transplantation improves grip strength in mice.

    “This decrease in grip strength was prevented in aged female mice that received either germ cell-containing or germ cell-depleted tissue transplants.”

    Animalsage-associated decrease in grip strengthgerm cell-containing or germ cell-depleted ovarian tissuefemales

    Aging-associated changes in motor function are ovarian somatic tissue-dependent, but germ cell and estradiol independent in post-reproductive female mice exposed to young ovarian tissue

    GeroScience

Tremor amplitude

downin mice1

1 study
  1. Young ovarian tissue transplantation decreases tremor amplitude in mice.

    “This increase in tremor amplitude was prevented in aged female mice that received ovarian tissue transplants”

    Animalsage-associated increase in tremor amplitudegerm cell-containing or germ cell-depleted ovarian tissuefemales

    Aging-associated changes in motor function are ovarian somatic tissue-dependent, but germ cell and estradiol independent in post-reproductive female mice exposed to young ovarian tissue

    GeroScience

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