Tetanus toxoid

Intervention1 paper6 findings

  • Animals1

Outcomes

6

TUNEL-positive cell count

downin mice1Very low certainty

1 study
  1. Tetanus toxoid decreases TUNEL-positive cell count in mice.

    Animalsbrain

    Tetanus vaccine ingredient improved learning and memory in aging mice · European journal of pharmacology · 6 Oct 2026

TUNEL-positive cell count →

Malondialdehyde

downin mice1Very low certainty

1 study
  1. Tetanus toxoid decreases malondialdehyde in mice.

    Animalsbrain

    Tetanus vaccine ingredient improved learning and memory in aging mice · European journal of pharmacology · 6 Oct 2026

Malondialdehyde →

Microglial M1-to-M2 phenotypic shift

upin mice1Very low certainty

1 study
  1. Tetanus toxoid induces microglial M1-to-M2 phenotypic shift in mice.

    Animalsbrain

    Tetanus vaccine ingredient improved learning and memory in aging mice · European journal of pharmacology · 6 Oct 2026

myelination

upin mice1Very low certainty

1 study
  1. Tetanus toxoid increases myelination in mice.

    Animalscorpus callosum, hippocampal hilus and striatum

    Tetanus vaccine ingredient improved learning and memory in aging mice · European journal of pharmacology · 6 Oct 2026

hippocampal neurogenesis

upin mice1Very low certainty

1 study
  1. Tetanus toxoid increases hippocampal neurogenesis in mice.

    Animalshippocampus

    Tetanus vaccine ingredient improved learning and memory in aging mice · European journal of pharmacology · 6 Oct 2026

Learning and memory

upin mice1Very low certainty

1 study
  1. Tetanus toxoid improves learning and memory in mice.

    Animals

    Tetanus vaccine ingredient improved learning and memory in aging mice · European journal of pharmacology · 6 Oct 2026

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European Journal of PharmacologyAnimals

Tetanus vaccine ingredient improved learning and memory in aging mice

An experiment in twelve-month-old mice found better learning and memory alongside more immature nerve cells and greater insulation around nerve…An experiment in twelve-month-old mice found better learning and memory alongside more immature nerve cells and greater insulation around nerve fibres.